Isolation a Lizard Leishmania promastigote from its Natural Host in Iran
نویسندگان
چکیده
منابع مشابه
natural promastigote infection of sergentomyja sintoni its seasonal variation and reservoir host in turkemen sahapa iran
a six month survey (may-october1994) was conducted, to study natural promastigote infection of s.sintoni, its seasonal variation and reservoir host, in turkemen sahra, iran. sixty out of 403 s.sintoni dissected were found infected with promastigotes. this investigation showed that the peak of promastigote infection occurs in july (18.4%) and august (28.5%). five lizards including one cyrtoopodi...
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Recent scientific evidence indicates that distinct patterns of susceptibility in BALB/c mice to Leishmania major infection are attributable to the differential expansion of distinct CD4+ T-cell subsets and their cytokines production. Production of the Th1 cytokine IFN-g is associated with resistance, whereas production of the Th2 cytokines IL-4 and IL-10 are associated with extreme susceptibili...
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The ability to screen compounds in a high-throughput manner is essential in the process of small molecule drug discovery. Critical to the success of screening strategies is the proper design of the assay, often implying a compromise between ease/speed and a biologically relevant setting. Leishmaniasis is a major neglected disease with limited therapeutic options. In order to streamline efforts ...
متن کاملComparison of the Lipophosphoglycan 3 Gene of the Lizard and Mammalian Leishmania: A Homology Modeling
Background: Lipophosphoglycan 3 (LPG3) is required for the LPG assembly, a well known virulent molecule. In this study, the LPG3 gene of the lizard and mammalian Leishmania species were cloned and sequenced. A three-dimensional structure (3D) for the target sequence was also predicted by comparative (homology) modeling. Materials and Methods: An optimization PCR amplification was performed o...
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ژورنال
عنوان ژورنال: Journal of Biological Sciences
سال: 2004
ISSN: 1727-3048
DOI: 10.3923/jbs.2004.620.623